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Erythromycin

US Brand Name Erythromycin
Generic Name Erythromycin Estolate
Other Brand Name Erycin, Althrocin, Erythrocin, Eltocin
Packing 10
Manufacturer Pfizer, Cipla, Alembic Pharma, Ipca Laboratorie
Form Tablet
Strength 250mg, 500mg
Country India

  • 50 tabs 250 mg $16.00
  • 50 tabs 500 mg $24.50
Available online
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  • Eltocin-DS, Erythromycin, Erythromycin Estolate 500mg
  • Erycin, Erythromycin Estolate 250 mg Packaging
  • Erycin, Erythromycin Estolate 250 mg Blister packaging
  • Erythromycin Tablet Box
  • Erycin, Erythromycin Estolate 250 mg tablet
  • Eltocin-DS, Erythromycin, Erythromycin Estolate 500mg tablet
  • Eltocin-DS, Erythromycin, Erythromycin Estolate 500mg tablet packaging
  • Eltocin-DS, Erythromycin, Erythromycin Estolate 500mg Storage condition
  • Eltocin-DS, Erythromycin, Erythromycin Estolate 500mg IPCA

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Erythromycin falls into a class of medications known as macrolide antibiotics. Macrolide antibiotic drugs retard the development of, or occasionally wipe out, sensitive bacteria by contracting the output of significant proteins required by the bacteria to exist.


Various Infections


Erythromycin is employed to address a wide variety of infections caused by bacteria. It is also used to check bacterial endocarditis, and onslaughts of rheumatic fever, mainly in children. Other infections include upper or lower respiratory airway infections, skin infections, severe pelvic inflammatory disease (inflammation of the female pelvic organs with symptoms like abdominal pain, fever and foul-smelling vaginal emission), erythrasma, etc.


Bacteria Causing Infections


All these infections are induced by bacteria such as Streptococcus pyogenes, Streptococcus pneumoniae, Mycoplasma pneumoniae, Staphylococcus aureus (causing maladies ranging from small-scale skin infections and abscesses, to severe diseases like pneumonia, meningitis and septicemia), Neisseria gonorrhoeae (the pus-creating bacterium that brings about gonorrhea), and lots of others.


Mechanism of Action


Erythromycin, similar to all macrolide antibiotic drugs, blocks bacterial cells from originating and procreating by intervening in their capability to produce proteins while not impacting human cells. Bacteria like Haemophilus influenzae are tolerant to Erythromycin when used single-handedly and should be applied with a mixture of Erythromycin and sufficient doses of sulfonamides.


Drug Indications


Erythromycin is indicated to address streptococcic contagions of the oral pharynx and tonsils (septic sore throat) and skin. It is recommended for the lung infections (pneumonia). Erythromycin is also indicated to take care of severe pelvic inflammatory disease, diphtheria (the shaping of a faux membrane in the throat and other air passages making breathing difficult), erythrasma, pertussis (whooping cough), listeriosis (an infectious disease affecting the central nervous system), and amoebiasis inside the intestines.
Erythromycin is used for the medical intervention of skin infections caused by staphylococcus bacteria and as a substitute antibiotic for the treatment of syphilis, gonorrhea, and chlamydia (a sexually transmitted infection). Other uses of Erythromycin are in patients who are hypersensitive to penicillin for the avoidance of frequent rheumatic fever and inflammation of the endocardium and hearts valves (endocarditis) and in patients with valvular deformities of the heart before they opt for dental therapies. The off-label uses for Erythromycin comprise acne, Lyme arthritis, and lockjaw.


Dosage & Administration


The standard dosage of Erythromycin for adults varies between 250 mg every 6 hours, 333 mg every 8 hours and 500 mg every 12 hours. Dosages may be raised up to 4 gram per day on the basis of the severity of the contagion.
In children under 12, the typical amount is 30 to 50 mg per kg everyday with age, weight, and harshness of the infection being taken into account to fix the suitable dosage.
Erythromycin may be consumed with or without foodstuff; nevertheless, optimum blood levels of this medicine are received when ingested empty-bellied (a minimum of half an hour and if possible 2 hours prior to or after meals).