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Clarithromycin Generic

US Brand Name Generic Biaxin
Generic Name Clarithromycin
Other Brand Name Klacid, Clarbact, Claribid
Packing 4,10
Manufacturer Alkem Laboratories, Pfizer, Ipca Laboratories, Abbott
Form Tablet
Strength 250mg, 500mg
Country India

  • 20 tabs 250 mg $38.00
  • 14 tabs 500 mg $40.60
Available online
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Introduction

Macrolide antibiotics are intended to fight against bacteria in human body. Clanthromycin is one of such marcolide antibiotics, which is used for treatment of various bacterial infections caused to the skin and respiratory system. It is also administered to persons having stomach ulcers caused by Helicobacter pylori, along with other medications.

Clarithromycin is a crystalline powder having a white to off-white color. It is insoluble in water, soluble in acetone and slightly soluble in methanol, ethanol, and acetonitrile. Under the brand name of Generic Biaxin, it comes in the form of immediate-release tablets, extended-release tablets, and granules for oral suspension.

Drug Indications

Generic Biaxin tablets are indicated for treatment of pharyngitis or tonsillitis due to streptococcus pyogenes, acute maxillary sinusitis and acute bacterial exacerbation of chronic bronchitis due to haemophilus influenzae, moraxella catarrhalis, or streptococcus pneumoniae. Community-acquired pneumonia due to haemophilus influenzae, mycoplasma pneumoniae, streptococcus pneumoniae, or chlamydia pneumoniae (TWAR) and uncomplicated skin and skin structure infections due to staphylococcus aureus, or streptococcus pyogenes are also treated with clanthromycin. It is also used for treating disseminated mycobacterial infections due to mycobacterium avium, or mycobacterium intracellulare.

Dosage & Administration

The dosages of Biaxin tablets are different for adults and pediatrics. The best dosages can be advised by your doctor. Adults suffering from Pharyngitis/Tonsillitis due to S. pyogenes should be prescribed a daily dose of 250 mg for 10 consecutive days. Adults suffering from acute maxillary sinusitis due to H. influenzae, M. catarrhalis and S. pneumoniae should be administered with a dosage of 500 mg divided in two doses, for 14 days.

The normal dosage for adults suffering from acute exacerbation of chronic bronchitis due to H. influenzae is 500 mg per day divided in two doses and should be administered for 7 to 14 days. In case of acute exacerbation of chronic bronchitis due to H. parainfluenzae, the normal daily dose is 500 mg divided in two and should be continued for 7 days. And for adults suffering from acute exacerbation of chronic bronchitis due to M. catarrhalis and S. pneumoniae, the normal dosage should be 250mg per day. The medication should be continued for 7 to 14 days.

The normal dosage for adults suffering from community-acquired pneumonia due to H. influenzae, S. pneumoniae and M. pneumoniae is 250 mg per day and should be administered for 7-14 days.

Side Effects

The most frequent side effects of Biaxin tablets seen with adults are diarrhea, nausea, abnormal taste, dyspepsia, abdominal pain/discomfort, and headache. In pediatric patients, the possible side effects are diarrhea, vomiting, abdominal pain, rash, and headache. Other possible side effects may include glossitis, stomatitis, oral moniliasis, anorexia, vomiting, pancreatitis, tongue discoloration, thrombocytopenia, leukopenia, neutropenia, and dizziness. You must immediately contact your doctor if the above said symptoms persist for long.

Drug Interactions

Clanthromycin is interactive with theophylline, verapamil belonging to the calcium channel blockers drug class, carbamazepine, terfenadine, omeprazole, ranitidine bismuth citrate and fluconazole and may lead to any kind of toxicity by increasing the plasma level. So, it is advisable to obtain the permission of a doctor before taking Biaxin tablets along with these drugs.

Drug Storage

Keep in cool dry place away from children and pet.