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Bicalutamide Generic

US Brand Name Casodex
Generic Name Bicalutamide
Other Brand Name Calutide
Packing 10
Manufacturer Cipla, Winthrop, Actavis
Form Tablet
Strength 50mg, 150mg
Country India

  • 28 tabs 50 mg $64.12
  • 28 tabs 150 mg $99.00
Available online
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Generic Bicalutamide is marketed by AstraZeneca under the trade name Casodex. It is a non-steroidal anti-androgen used orally in the hormonal treatment of prostate cancer and hirsutism (too much hairiness). It was initially launched in the year 1995 as an adjunctive therapy (with surgical or medical castration or removal of the testes) for prostate cancer in advance stages and afterwards introduced as a monotherapy for the management of earlier stages of this ailment.

Mode of Action

Hormonal treatments generally hinder the output or activity of specific hormones in our system. Hormones are substances secreted in the body by natural means. They function as chemical transmitters and assist in regulating the actions of cells and different bodily parts.

Casodex resembles the structure of the male sex hormone testosterone or androgenic hormone. It acts by keeping testosterone from adhering (attaching) to the receptors on the walls of the prostate cancer cells. With the absence of testosterone, the cancer cells either grow more tardily or impede growing completely. The cancer may reduce in magnitude consequently.

Dosage & Administration

Casodex (Bicalutamide) is supplied in the form of a tablet, which is received one time per day. It is obtainable in two diverse strengths: 50 mg and 150 mg. Take the pill by mouth precisely as instructed by your physician, generally either in the morning or in the evening. It would be an excellent step to take this drug at the same instant every day. Casodex may be received with or without meals. Do not add to your dose or quit taking this medicinal drug without first discussing with your medical practitioner.

Time to Start Treatment

Bicalutamide may be employed to address prostate cancer that has started to widen into the tissues surrounding the prostate gland (topically advanced). It can either be administered as a monotherapy or after surgical process or radiation therapy.

In case of prostate cancer that has extended to other areas of the body (advanced or metastatic cancer), Casodex may be administered in association with injections of a different kind of hormonal-therapy medication (known as a pituitary down regulator), for instance goserelin, buserelin, triptorelin or leuprorelin. These medications inhibit the output of a hormone generated by the pituitary gland (leuteinising hormone), which arouses the output of testosterone.

Potential Side Effects

Some of the common side effects of Casodex may include breast swelling and tenderness (gynaecomastia), hot flushes, itchiness and desiccation of the skin, nausea (sickness), reduced libido or sexual desire, erectile dysfunction or impotence, feelings of weakness, or putting on weight, particularly around the chest or waist. Rare side effects of Bicalutamide may comprise general pain in the abdomen or back, or changes in liver function. Inform your healthcare provider if you have had any liver problems in the past. Your doctor may have to carry out blood tests on a regular basis to ensure Casodex has no adverse impact on your liver.

Duration of Treatment

Your physician will talk about the duration of treatment that they find suitable for your condition. Casodex is most often administered for more than a few months or years. This hormonal therapy may carry on as long as it is effectual in checking your prostate cancer.