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Clindamycin Gel Generic

US Brand Name Cleocin-T
Generic Name Clindamycin Phosphate
Other Brand Name Clincitop, Clindac-A, Climple, Clinka
Manufacturer Intas, Universal, Galderma, Cadila Pharma
Packing 15g, 20g
Form Gel
Strength 1%

  • 20g 1% $4.99
  • 15g 1% $4.70
Available online
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Introduction

An antibiotic is produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. And Clindamycin phosphate is a water soluble ester of the so produced semi-synthetic antibiotic. Under the brand name of Generic Cleocin-T, it comes as a gel for topical use. The Cleocin-T Gel comprises of Clindamycin phosphate, USP, at a concentration equivalent to 10 mg Clindamycin per gram. It is composed of allantoin, carbomer 934P, methylparaben, polyethylene glycol 400, propylene glycol, sodium hydroxide, and purified water.

Drug Indications

Cleocin-T topical solution, topical gel and topical lotion are indicated for the treatment of acne vulgaris. It is caused by the over active oil glands which become plugged, red, and inflamed. It is very common in teenagers or young adults. It is also called pimples.

How It Works

In vitro, Clindamycin phosphate is inactive and in vivo, it gets converted into the antibacterially active Clindamycin. It cross resists lincomycin and antagonizes erythromycin.

Following multiple topical applications of Clindamycin phosphate at a concentration equivalent to 10 mg Clindamycin per mL in an isopropyl alcohol and water solution, very low levels of Clindamycin are present in the serum (0-3 ng/mL) and less than 0.2% of the dose is recovered in urine as Clindamycin.

Dosage & Administration

It should be administered as directed by your physician or you can follow the instructions inscribed on the instruction manual which comes along with the gel. A thin coat of the Cleocin-T gel should be applied on the affected area. It should be used twice daily. Before using the gel, the affected area should be cleaned and dried up. After applying the topical, your hands must be washed with water if they do not form the part of treatment.

Because the gel is for external use only, it should not be swallowed and should be kept away from coming in contact with eyes. If it gets into your eyes accidentally, then seek immediate medical help.

Side Effects

Because Clindamycin Phosphate Gel is a topical for skin, its most common side effects are associated with skin and they are burning, itching, peeling skin, reddened skin and skin dryness. The other possible side effects are diarrhea, bloody diarrhea and colitis (including pseudomembranous colitis), abdominal pain and gastrointestinal disturbances as well as gram-negative and folliculitis.

Drug Interactions

Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore it should be used with caution in patients receiving such agents.

Drug Precautions

Cleocin-T gel should be avoided from coming contact with eyes. It contains an alcohol base which will cause burning and irritation of the eye. In the event of accidental contact with sensitive surfaces (eye, abraded skin, mucous membranes), bathe with enough amounts of cool tap water. While applying around the mouth, one has to be careful enough to not let get into the mouth. It may cause harm as it has been only designed for external use.

This drug can be used during pregnancy only after obtaining the permission of your doctor.

Because, orally and parenterally administered Clindamycin has been reported to appear in breast milk. So, nursing mothers need to consult their physicians before using the Cleocin-T gel.

The patients under the age of 12 years should not be prescribed with this medication as its safety and effectiveness in relation to them have not yet been established.