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Prochlorperazine Maleate Generic

US Brand Name Generic Comapazine
Generic Name Prochlorperazine Maleate
Other Brand Name Acuvert, Stemetil MD
Packing 21
Manufacturer Piramal Healthcare
Form Tablet
Strength 5 mg
Country India

  • 50 tabs 5 mg $24.50
Available online
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  • Acuvert, Prochlorperazine
  • Generic Comapazine, Prochlorperazine Maleate  5mg ( Stemetil MD  )

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Active ingredient: Prochlorperazine Maleate


Being a phenothiazine derivative, Prochlorperazine is present in tablets as the maleate. It is a viscous liquid having a clear, pale yellow color and readily dissolves in alcohol, chloroform and ether and is slightly soluble in water. Falling under the category of antiemetic and antipsychotic tranquilizer, the Prochlorperazine Maleate is available in the form of tablets to be administered orally under the trade name of Generic Comapazine. Each Comapazine tablets is round in shape and yellow green in color containing 5 mg of Prochlorperazine Maleate and imprinted with SKF and C66.


The Generic Comapazine tablets are indicated for treating nausea and vomiting. It is also prescribed for the patients suffering from schizophrenia.

Dosage And Administration:

Dosage for adults:

The dosage of Generic Comapazine should be decided depending on the responsiveness of the patient to the drug. In debilitated or emaciated patients, the dosage should be increased more gradually.

The normal dosage of Prochlorperazine Maleate for adults suffering from severe nausea and vomiting is a single dose of 15 to 30 mg day. Only in resistant cases, the dosage may be 40 mg per day and should be taken as a single dose.

The normal dosage for adults suffering from psychiatric disorders, especially non-psychotic anxiety is 15 mg to 20 mg per day. The dosages should be adjusted as per the responsiveness of the patient and severity of the disease but should not exceed 20 mg per day.

For patients suffering from psychotic disorders including Schizophrenia and are in relatively mild conditions, a dose of 5 or 10 mg may be given for three to four times in a day.

Patients with moderate to severe conditions and are hospitalized or adequately supervised, should be administered with an initial dosage of 30 to 40 mg per day. The dosage may be gradually increased as per requirement by small amounts at a gap of two or three days. The maximum dose is of 100-150 mg per day.

Dosage for children:

Children below the age of two years and below the weight of 20 pounds should not be prescribed with this medicine. The dosages for children suffering from nausea and vomiting depend on the severity of the symptoms and the response of the patient. Children with weight ranging from 20 to 29 lbs, should be given a dose of 2 1/2 mg 1 or 2 times a day and should not exceed 7.5 mg per day, 30 to 39 lbs should be given a dose of 2 1/2 mg 2 or 3 times a day and should not exceed 10 mg per day and children falling in the weight range of 40 to 85 lbs should be administered with a dosage of 2 1/2 mg 3 times a day or 5 mg 2 times a day and the dosage should not be more than 15 mg per day at any cost.

For children with schizophrenia, a dosage of 21/2 mg 2 or 3 times daily should be administered to the children from 2-12 years of age. The total daily dose should not exceed 20 mg per day in case of children from 2-5 years of age and 25 mg per day in case of children from6 to 12 years of age.


In case you have used overdose, make contact with your local poison control center without delay.

Missed Dose

If you seem to miss a dose, take it immediately you remember. But you should not take double dose to make up the missed dose.

Side Effects:

The symptoms of dizziness, drowsiness, dry mouth, throat, and nose, thickening of mucus in nose or throat, severe allergic reactions like rash, hives, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue, chest pain, convulsions, decreased alertness, difficulty urinating, excessive excitability, fast or irregular heartbeat, fever, hallucinations, mental or mood changes, pounding in the chest; seizures, tremor, unusual bruising or bleeding, wheezing and yellowing of the eyes or skin are the side effects of the Generic Comapazine tablets. If you experience any of the above said symptoms, then immediately call for your doctor.

Drug Interaction

Compazine® (prochlorperazine maleate) can give rise to interaction with many other drugs. The following drugs that may lead to Compazine interactions are barbiturates, alcohol, narcotics or opiates, seizure medications, propranolol (Inderal®, innopran XL®, Inderal la®), warfarin (Coumadin®, jantoven®).


Store Prochlorperazine Maleate tablets in a cool, dry place, away from heat and light but do not store in bathroom. Keep away from the reach of children and pets.