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Ofloxacin Generic

US Brand Name Generic Floxin
Generic Name Ofloxacin
Other Brand Name Oflox, Zanocin, Xioflo, ZO
Packing 10
Manufacturer Aventis, Protec, Ranbaxy, Cipla, Sun Pharma, Aeran Lab India, FDC
Form Tablet
Strength 100 mg, 200 mg, 400 mg
Country India

  • 10 tabs 100 mg $13.50
  • 10 tabs 200 mg $19.90
  • 10 tabs 400 mg $27.90
Available online
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Introduction

Under the category of fluoroquinolones, Ofloxacin is an antibiotic which fights bacteria in the body. It is a fluorinated carboxyquinolone used for treatment of bronchitis, pneumonia, chlamydia, gonorrhea, skin infections, urinary tract infections, and infections of the prostate which are caused due to bacteria. It is off-white to pale yellow crystalline powder which dissolves with aqueous solutions with pH between 2 and 5 and sparingly and slightly dissolves with aqueous solutions with pH 7. Aqueous solutions having pH 9 and above have a free solubility with it.

Having the potentiality of forming stable coordination compounds with many metal ions, Ofloxacin comes in the form of tablets for oral administration, under the brand name of Generic Floxin. Each Generic Floxin tablet comprises of anhydrous lactose, modified corn starch, hydroxypropyl cellulose, hypromellose, magnesium stearate, polyethylene glycol, polysorbate 80, sodium starch glycolate, titanium dioxide and may also contain synthetic yellow iron oxide along with Ofloxacin.

Dosage & Administration

This medication should be taken exactly the way as it has been directed by your doctor. You can also administer yourself with the dosage prescribed on the medicine label. The Floxin tablets can be taken with a full glass of water after food or empty stomach but it should be at the same time every day.

The normal dosage for patients suffering from acute bacterial exacerbation of chronic bronchitis, commonly acquired pneumonia and uncomplicated skin and skin structure infections is 800 mg per day divided in two doses. The medication should be continued for 10 consecutive days.

The normal dosage for patients suffering from nongonococcal cervicitis/urethritis due to H.trachomatis, mixed infection of the urethra and cervix due to C.trachomatis and N.gonorrhoeae, prostatitis due to E.coli is 600 mg per day in two divided doses. The drug should be administered for 7 days continuously.

For patients suffering from uncomplicated cystitis due to E.coli or K.pneumoniae and uncomplicated cystitis due to other approved pathogens is 200 mg per dose and should be taken twice in a day. The medication should be continued for 3 consecutive days in the former case and for 7 consecutive days in the later case.

Side Effects

The most common side effects of this drug are nausea, headache, insomnia, external genital pruritus in women, dizziness, vaginitis, diarrhea, and vomiting. Some times symptoms of abdominal pain and cramps, chest pain, decreased appetite, dry mouth, dysgeusia, fatigue, flatulence, gastrointestinal distress, nervousness, pharyngitis, pruritus, fever, rash, sleep disorders, somnolence, trunk pain, vaginal discharge, visual disturbances, and constipation develop as side effects to the consumption of Generic Floxin tablets.

Drug Interactions

Ofloxacin is interactive with antacids, sucralfate, metal cations, multivitamins, cimetidine, cyclosporine, drugs metabolized by cytochrome p450 enzymes, non-steroidal anti-inflammatory drugs, probenecid, theophylline, warfarin and antidiabetic agents like insulin, glyburide/glibenclamide. So, a dose adjustment may be required while consuming these drugs along with Generic Floxin tablets.

Drug Contradictions

Consumption of Floxin tablets is contradicted for the persons who already have a history of hypersensitivity associated either with the use of Ofloxacin or any other member of the quinolone group of antimicrobial agents.

Storage Tips

It should be stored at room temperature, away from heat and light. Contact with moisture should be avoided. It should always be kept away from the reach of children and pet.