Metformin, Careprost, Sildenafil, Tadalafil

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Sildenafil Generic

US Brand Name Revatio
Generic Name Sildenafil
Other Brand Name Assurans
Packing 10
Manufacturer Cipla
Form Tablet
Strength 20 mg

  • 30 tabs 20 mg $29.10
Available online
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  • Assurans, Generic Revatio, Sildenafil 20 mg Tablet (Cipla)
  • Assurans, Generic Revatio, Sildenafil 20 mg Tablet, (Cipla) Patient Information sheet 1
  • Assurans, Generic Revatio, Sildenafil 20 mg Tablet (Cipla) Patient Information sheet 2
  • Assurans, Generic Revatio, Sildenafil 20 mg Tablet (Cipla) Box
  • Generic Revatio, Sildenafil Tablet composition
  • Generic Revatio, Sildenafil Tablet
  • Generic Revatio, Sildenafil Tablet blister pack information
  • Assurans, Generic Revatio, Sildenafil Information Sheet 1
  • Assurans, Generic Revatio, Sildenafil Information Sheet 2

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Introduction :

Sildenafil is an inhibitor of phosphodiesterase type 5 and relaxes muscles and increases blood flow to particular areas of the body. Sildenafil citrate is a white to off-white crystalline powder and has a solubility of 3.5 mg/mL in water. It bears a molecular weight of 666.7. Carrying the brand name of Generic Revatio, it is available in the form of tablets for oral administration. Generic Revatio tablets are used for treating pulmonary arterial hypertension and improving exercise capacity in men and women and are used for treating erectile dysfunction (impotence) in men. Microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose monohydrate, and triacetin are inactive ingredients of these tablets.

Indication :

Generic Revatio tablets are indicated for the treatment of pulmonary arterial hypertension (WHO Group I) for improving exercise ability and delay clinical worsening. The delay in clinical worsening was confirmed when Sildenafil was added to background epoprostenol therapy.

Mechanism Of Action :

In the smooth muscle of the pulmonary vasculature, where PDE5 is responsible for degradation of cGMP, Sildenafil inhibits the cGMP specific phosphodiesterase type-5 (PDE5) and PDE5 is responsible for degradation of cGMP. By increasing cGMP within pulmonary vascular smooth muscle cells, Sildenafil results in the relaxation of the muscle cells. In case of patients suffering from pulmonary hypertension, the drug can lead to vasodilation of the pulmonary vascular bed and vasodilatation in the systemic circulation, to a lesser degree.

Dosage And Administration :

The dosage and administration of the Generic Revatio as directed by your doctor or as per instructions on the tablet strip.

Patients with pulmonary arterial hypertension (PAH) may be administered with a dose of 20mg three times a day. The doses should be taken at intervals of 4-6 hours. These tablets can be taken with or without food. Higher doses than 20 mg TID is not advisable as any greater efficacy with that dose has not yet been achieved.

Side Effects :

The serious side effects of Generic Revatio tablets are hypotension, vision loss, hearing loss and priapism. Paresthesia, headache, sinusitis, dyspepsia, gastritis, flushing, pyrexia, insomnia, myalgia, erythema, diarrhea, rhinitis and dyspnea exacerbated are side effects of the drug with less severity.

Side effects may be more than what have been stated here, so any unusual health symptom should be immediately reported to your doctor.

Drug Interaction:

Sildenafil is interactive with various drugs. So, it is important that you should reveal to your doctor about all other medicines you are going to consume along with these tablets.

Concomitant use of the drug with potent CYP3A inhibitors and ritonavir is not recommended. Alpha-blockers should be carefully administered with these tablets as they may add to blood pressure-lowering effects. With amlodipine, the drug showed additional reduction on supine blood pressure.

Drug Contraindication:

Generic Revatio tablets are contraindicated from being used with organic nitrates as they can potentiate the hypotensive effects of nitrates. So, individuals who are taking organic nitrates should not be administered with these tablets. These tablets are contraindicated in patients who have a known hypersensitivity to Sildenafil or any other component of these tablets.

Storage :

Generic Revatio tablets come with film-coated and are recommended to be stored at room temperature ranging from15-30°C or 59-86°F. Avoid contact of these tablets with direct heat, light and moisture. Store these tablets away from the reach of children and pets.