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Premarin, Conjugated Estrogens

US Brand Name Premarin
Generic Name Conjugated Estrogen
Other Brand Name Premarin
Packing 28
Manufacturer Wyeth, Pfizer
Form Tablet
Strength 0.625 mg
Country Ireland, UK, India

  • 84 Tabs 1.25mg (WYETH) $61.70
  • 28 Tabs 0.3mg (WYETH) $34.46
  • 84 Tabs 0.625 mg $58.00
Available online
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  • Premarin, Conjugated Estrogens 0.625 mgTablet (Wyeth)
  • Premarin,  Conjugated Estrogens 0.625 Mg Tablet (Wyeth)
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  • Premarin, Conjugated Estrogens 0.625 mg Tablet Box
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Active ingredient: Conjugated Estrogens

Introduction

Premarin is an oral medication that can be obtained on prescription from a medical practitioner only. It comprises a concoction of estrogen hormones, also known as conjugated estrogens. The estrogens, a common phrase for female steroid sex hormones, are not artificial but obtained from a natural resource.

Drug Uses

Premarin falls into a group of medicines employed for hormone replacement therapy (HRT) and is most of the time applied to care for the signs related to menopause, in addition to other estrogen linked conditions like breast cancer. It is also used for the avoidance of osteoporosis in women subsequent to menopause. Premarin is supplied in oral tablet as well as cream form and is administered in various strengths. Hormone therapy comprising only estrogen is normally indicated for females having no uterus; females having a uterus characteristically derive a benefit from compounded estrogen-plus-progestin hormonal therapy.

Mechanism of Action

All through menopause, a large number of women feel irritating signs because of the falling estrogen levels. These signs include hot flashes, dryness of the vagina and mood-associated symptoms. Opting for estrogen replacement therapy, patients can witness relief from these symptoms in many cases. Besides, this hormone replacement therapy can ameliorate bone denseness in females at considerable risk for abnormal loss of boney tissues happened in osteoporosis.

Dosage & Administration

Make a clear understanding of how Premarin is directed for use. It is usually prescribed in 0.3 milligram pills to be ingested one time per day. Now and again, it is recommended in a cyclic regime, which is 5 days of stoppage after taking Premarin continuously for 25 days. Since the effectiveness deviates from person to person, comply with the instructions given by your doctor in an attentive manner. In addition, be aware of how it functions. Premarin is soaked up promptly in the stomach and can be received with or without food and water.

Keep an eye on your levels of estrogen. The lowest degree of estrogen that is effectual for your body must be sustained after menopausal symptoms are in check. Your healthcare provider must reassess you regularly to fix the required dose of Premarin. This is typically carried out at 3 to 6 month gaps.

Drug Interactions

Premarin may interact with a number of general medications, food items and herbal supplementations to generate undesirable effects. Hydrocortisone and anticoagulant medications elevate the effect of estrogen. Antiepileptics, in addition to Rifampin, Ritonavir and Nelfinavir, reduce the effect of estrogen. Females using Premarin must evade the everyday use of ethyl alcohol, St. John's Wort, black cohosh, dong quai, purple clover, scrub palmetto and panax ginseng.

Drug Warnings

Premarin, coagulated estrogen tablets may create headaches, pain in the breast, abnormal vaginal bleeding, stomach spasms and swelling up, unsettled stomach and disgorgement, hair loss, fluid retention and yeast infections in the vagina. These harmful effects are reasonably common, but not severe, and habitually diminish with time.

More dangerous side effects of Premarin therapy include breast cancer, uterine cancer, or ovarian cancer; blood clots resulting in heart failure or stroke; hypertension; high blood glucose; and liver disorders. These side effects take place on the odd occasion, but warning signals, such as abnormal localized breast enlargement, vertigo, shifts in speech or eyesight, pain in the chest, breathlessness, or yellowing of the skin or eyes, must be informed to your medical practitioner instantaneously.