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Trivastal LA, Piribedil

US Brand Name Trivastal
Generic Name Piribedil
Other Brand Name Trivastal LA
Packing 10
Manufacturer Serdia Pharmaceuticals India
Form Tablet
Strength 50 mg
Country India

  • 10 tabs 50 mg $10.90
Available online
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Trivastal L.A. is the brand name for Piridedil. Other brand names of this drug are Pronoran, Trivastan and Trastal. This drug is an antiparkinsonian factor and piperazine offshoot. It is both a D2 and D3 receptor agonist. This medicine also features α2 -adrenergic antagonist attributes.


Label Indication

TRIVASTAL L.A. is useful in two most important pathologies: cerebral aging and Parkinson's disease. This medicine can be used to treat age associated mild cognitive impairment which brings the symptoms such as vigilance loss, loss of memory, concentration, weal intellectual utility and vertigo.
Parkinson's disease can be treated using this drug either alone or in conjunction with L-DOPA treatment, in the preliminary stages plus in the advanced stages of the condition.

Unlabelled Indication

This medication is also helpful in many other conditions. It has also been proved effective in improving memory capacities in common aging adults. In age-associated memory problem, it influences psychophysiological condition of elderly people and enhances memory and the velocity of psychomotor reactions and lability of nervous systems. It also works well in restless legs syndrome.


Parkinson's disease

For Parkinson's disease, the patient should take one tablet of Trivastal L.A daily during the first week. Then your doctor can advise you an increased dose every week until the most favorable therapeutic dose is achieved:

If this medicine is taken alone, a dose of three to five tablets daily is recommended to be taken at different times in a day. If the doctor has told you to take it in conjunction with L-dopa therapy, you may be asked to take one to three tablets daily.

Other Conditions

If you are taking this drug for other disease, you can take one tablet daily after main meal. In severe cases, you may be recommended for two tablets every day in two doses.

Adverse Reactions

Use of Trivastal L.A may lead to some undesirable adverse reactions such as minor gastrointestinal upset (vomiting, nausea, flatulence, etc) in liable individuals, or while received between meals. Here, individual adjustment of the dose, and/or adding of domperidone (Motilium) can be considered. This drug may also come up orthostatic hypotension or drowsiness, mainly in predisposed people.

Drug Interactions

This medicine should not be used together with several other drugs such as Dopamine antagonists as it may decrease the usefulness of Piridedil.


Chances are there that this drug can damage your thinking or reactions. Be cautious when you drive or do any works calling for you to be alert and wakeful. Stay away from alcohol intake, which can enhance some of the adverse effects of Piridedil.

Do not get up quickly from a sitting or lying pose to avoid dizziness and prevent a fall.

Furthermore, lie down at the first symptom of lightheadedness, dizziness, or weakness.

Never abruptly discontinue taking it without first discussing with your doctor.

This drug may reduce the efficacy of your birth control medication. To avoid pregnancy, you should adopt another type of birth control (e.g., condoms) while you are being treated with this drug.

You may be needed to make lab test of liver and kidney function, blood and heart function, to check your progress.

Ask your doctor before giving it to children younger than 15 years of age and pregnant and breast-feeding women.